Yihong Ye Selected Research

1- (4- chlorophenyl)- 3- (3- (4- chlorophenyl)- 5,5- dimethyl- 1- (3- (5- nitrofuran- 2- yl)allyldienehydrazinocarbonylmethyl)- 2- oxoimidazolidin- 4- yl)- 1- hydroxyurea

11/2016	Eeyarestatin I derivatives with improved aqueous solubility.
11/2010	The ERAD inhibitor Eeyarestatin I is a bifunctional compound with a membrane-binding domain and a p97/VCP inhibitory group.

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Yihong Ye Research Topics

Disease

7	Neoplasms (Cancer) 01/2019 - 02/2009
3	COVID-19 01/2022 - 09/2020
3	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 05/2006
3	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 08/2011 - 02/2009
2	Neurodegenerative Diseases (Neurodegenerative Disease) 05/2022 - 01/2018
2	Starvation 01/2021 - 01/2018
2	Multiple Myeloma 11/2010 - 02/2009
1	Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis) 05/2022
1	Disease Progression 01/2022
1	Breakthrough Infections 01/2022
1	Infections 01/2022
1	Tauopathies 01/2021
1	Anemia 01/2020
1	Parkinson Disease (Parkinson's Disease) 01/2020
1	Cicatrix (Scar) 01/2020
1	Carcinogenesis 11/2015
1	Dystonia musculorum deformans type 1 07/2011
1	Machado-Joseph Disease (Spinocerebellar Ataxia Type 3) 07/2011
1	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 09/2006

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 05/2022 - 09/2006
4	Pharmaceutical PreparationsIBA 11/2020 - 02/2009
3	Bortezomib (Velcade)FDA Link 08/2011 - 02/2009
2	SynucleinsIBA 05/2022 - 01/2020
2	UbiquitinIBA 01/2021 - 02/2009
2	Valosin Containing ProteinIBA 01/2019 - 11/2016
2	1- (4- chlorophenyl)- 3- (3- (4- chlorophenyl)- 5,5- dimethyl- 1- (3- (5- nitrofuran- 2- yl)allyldienehydrazinocarbonylmethyl)- 2- oxoimidazolidin- 4- yl)- 1- hydroxyureaIBA 11/2016 - 11/2010
2	ATPases Associated with Diverse Cellular ActivitiesIBA 07/2011 - 11/2010
2	Ataxin-3IBA 07/2011 - 09/2006
2	Proteasome InhibitorsIBA 11/2010 - 02/2009
2	PresenilinsIBA 08/2007 - 05/2006
1	Green Fluorescent ProteinsIBA 05/2022
1	palmitoyl-protein thioesteraseIBA 05/2022
1	Carrier Proteins (Binding Protein)IBA 05/2022
1	Cysteine (L-Cysteine)FDA Link 05/2022
1	Glutamine (L-Glutamine)FDA Link 05/2022
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 05/2022
1	LipofuscinIBA 05/2022
1	Phosphotransferases (Kinase)IBA 05/2022
1	StreptavidinIBA 05/2022
1	Sirolimus (Rapamycin)FDA Link 05/2022
1	Heavy Chain Fusion Regulatory Protein 1IBA 05/2022
1	Small Interfering RNA (siRNA)IBA 05/2022
1	bafilomycin A1IBA 05/2022
1	ClusterinIBA 05/2022
1	Lysosomal-Associated Membrane Protein 1IBA 05/2022
1	Endosomal Sorting Complexes Required for TransportIBA 05/2022
1	Heparitin Sulfate (Heparan Sulfate)IBA 01/2022
1	VaccinesIBA 01/2022
1	Mitoxantrone (Novantrone)FDA LinkGeneric 01/2022
1	DNA TopoisomerasesIBA 01/2022
1	Protein AggregatesIBA 01/2021
1	IntegrinsIBA 01/2021
1	Ligases (Synthetase)IBA 01/2021
1	Lysine (L-Lysine)FDA Link 01/2021
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2021
1	ClathrinIBA 01/2020
1	Adenosine Triphosphatases (ATPase)IBA 11/2015
1	AntioxidantsIBA 08/2011
1	polyglutamineIBA 07/2011
1	CalpainIBA 07/2011
1	Proteasome Endopeptidase Complex (Proteasome)IBA 02/2009
1	Deubiquitinating EnzymesIBA 09/2006
1	Flavin-Adenine Dinucleotide (FAD)IBA 05/2006

Therapy/Procedure

5	Therapeutics 01/2022 - 02/2009